The aim of this research to asset the impact of source of funds to profitability at PT. Bank Danamon Indonesia,Tbk. Primary data gotten from funds source income year 2004-2008. Funds source measured from debt equity ratio, and instrumen analysis of profitability is rentability of equity. Meanwhile secondary data plotted from Bank Danamon Financial report. By regression analysis known regression equition Y (rentability of equity) = 8,508-0,093 X (debt to equity ratio). Regression coefficient-0.093 means every increase of debt to equity ratio in 1%, will decrease rentability of equity 0.093. Than impact of debt to equity ratio significantly to rentability of equity at confident level 95%.