Actually, the holy al-Quran is the speech of Allah, that it unifies with Allah before embodying to the prophet Muhammad. When the holy al-Quran has entered to the humanity area , it had entered to the cultural world. Because the transformation of al-Quran through the cultural process. The mushaf al-Quran was know until now , actually the part of the cultural and humanity. The quranic exegeses was not a quran it self because in the quranic exegeses there are some penetration of humankind. This article will elaborate the relation between al-Quran and cultural studies.